2-Chloroethanol → 2-(Pyridin-3-yloxy)ethan-1-ol

HRID 75474

반응식

HRID 75474 반응식
[OH:1][C:2]1[CH:3]=[N:4][CH:5]=[CH:6][CH:7]=1.Cl[CH2:9][CH2:10][OH:11].C([O-])([O-])=O.[K+].[K+]>CN(C=O)C>[N:4]1[CH:5]=[CH:6][CH:7]=[C:2]([O:1][CH2:9][CH2:10][OH:11])[CH:3]=1

참가 물질

5

반응물 3

HCID 342-ChloroethanolHCID 79713-HydroxypyridineHCID 11430Potassium Carbonate

생성물 1

HCID 219089972-(Pyridin-3-yloxy)ethan-1-ol

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

The yield of the title compound according to D1, starting from 3-hydroxypyridine, 2-chloroethanol and K2CO3 in DMF was 19%. The title compound has also been prepared according to EP 0 286 242 A2 starting from methyl [(3-pyridinyl)oxy]acetate.

출처 및 근거

ORD 기록
ord-b440f9e1831244a0b541a4df6290b27d
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08835439B2

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