Dodecanoyl chloride → Dodecanoic acid, 2-(dimethylamino)-1-methylethyl ester

HRID 78384노트

반응식

HRID 78384 반응식
[C:1](Cl)(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].C(N(CC)CC)C.[CH3:22][N:23]([CH2:25][CH:26]([OH:28])[CH3:27])[CH3:24]>C(Cl)(Cl)Cl>[C:1]([O:28][CH:26]([CH3:27])[CH2:25][N:23]([CH3:24])[CH3:22])(=[O:13])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

참가 물질

5

반응물 3

HCID 8166Dodecanoyl chloride2회HCID 8471Triethylamine2회HCID 37511Dimepranol

생성물 1

HCID 157516Dodecanoic acid, 2-(dimethylamino)-1-methylethyl ester

시약·촉매·용매 1

HCID 6212Chloroform용매2회

실험 절차

The (N,N-disubstituted amino)-alkanol alkanoates are readily prepared by reacting the corresponding aminoalkinol with lauroyl chloride in the presence of triethylamine. A solvent such as chloroform is optional but preferred. For example, 1-(N,N-dimethylamino)-2-propanol can be reacted with lauroyl chloride in chloroform and in the presence of triethylamine to form 1-(N,N-dimethylamino)-2-propanol dodecanoate (DAIPD).

출처 및 근거

ORD 기록
ord-bf52ec518a5245d2b9e2bd2b666bbaa9
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08841345B2

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