Ethanolamine → 2-(5-tert-butyl-2-iminothiazol-3(2H)-yl)ethanol

HRID 78541노트

반응식

HRID 78541 반응식
[CH3:1][C:2]([CH3:7])([CH3:6])[CH2:3][CH:4]=O.[NH2:8][CH2:9][CH2:10][OH:11].[S-:12][C:13]#[N:14].[K+].II>>[C:2]([C:3]1[S:12][C:13](=[NH:14])[N:8]([CH2:9][CH2:10][OH:11])[CH:4]=1)([CH3:7])([CH3:6])[CH3:1]

참가 물질

5

반응물 4

HCID 700EthanolamineHCID 807IodineHCID 763353,3-DimethylbutanalHCID 516872Potassium thiocyanate

생성물 1

HCID 686223382-(5-tert-butyl-2-iminothiazol-3(2H)-yl)ethanol

실험 절차

Commercially available 3,3-dimethylbutanal (Aldrich), 2-aminoethanol (Aldrich), potassium thiocyanate (Aldrich) and iodine (EMD chemicals) were processed using the method described in Example 315A to afford the title compound. MS (ESI+) m/z 201 (M+H)+.

출처 및 근거

ORD 기록
ord-fa97ec1a5cae4794a531f146053df4aa
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08841334B2

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