4-Methylmorpholine → [1-(6-{5-[4-(6-{2-[4-Cyano-1-(2-methoxycarbonylamino-butyryl)-pyrrolidin-2-yl]-3H-imidazol-4-yl}-naphthalen-2-yl)-phenyl]-1H-imidazol-2-yl)-5-aza-spiro[2.4]heptane-5-carbonyl)-2-methyl-propyl]-carbamic acid methyl ester

반응식

[CH3:1][O:2][C:3]([NH:5][CH:6]([CH2:10][CH3:11])[C:7](O)=[O:8])=[O:4].C1C=CC2N(O)N=NC=2C=1.Cl.Cl.Cl.[CH3:25][O:26][C:27](=[O:75])[NH:28][CH:29]([C:33]([N:35]1[CH:41]([C:42]2[NH:43][C:44]([C:47]3[CH:52]=[CH:51][C:50]([C:53]4[CH:62]=[CH:61][C:60]5[C:55](=[CH:56][CH:57]=[C:58]([C:63]6[NH:64][C:65]([CH:68]7[CH2:72][CH:71]([C:73]#[N:74])[CH2:70][NH:69]7)=[N:66][CH:67]=6)[CH:59]=5)[CH:54]=4)=[CH:49][CH:48]=3)=[CH:45][N:46]=2)[CH2:40][C:37]2([CH2:39][CH2:38]2)[CH2:36]1)=[O:34])[CH:30]([CH3:32])[CH3:31].CN1CCOCC1>CN(C=O)C.CCOC(C)=O>[CH3:25][O:26][C:27](=[O:75])[NH:28][CH:29]([C:33]([N:35]1[CH:41]([C:42]2[NH:43][C:44]([C:47]3[CH:48]=[CH:49][C:50]([C:53]4[CH:62]=[CH:61][C:60]5[C:55](=[CH:56][CH:57]=[C:58]([C:63]6[NH:64][C:65]([CH:68]7[CH2:72][CH:71]([C:73]#[N:74])[CH2:70][N:69]7[C:7](=[O:8])[CH:6]([NH:5][C:3]([O:2][CH3:1])=[O:4])[CH2:10][CH3:11])=[N:66][CH:67]=6)[CH:59]=5)[CH:54]=4)=[CH:51][CH:52]=3)=[CH:45][N:46]=2)[CH2:40][C:37]2([CH2:38][CH2:39]2)[CH2:36]1)=[O:34])[CH:30]([CH3:32])[CH3:31]