Hydrochloric Acid → 4-(4-Methylpiperazin-1-yl)-6-[2-(pyrrolidin-1-ylcarbonyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyrimidin-2-amine

반응식

[CH3:9][N:10]1[CH2:11][CH2:12][N:13]([c:16]2[n:17][c:18]([NH2:32])[n:19][c:20](-[c:22]3[cH:23][cH:24][c:25]4[c:30]([cH:31]3)[CH2:29][NH:28][CH2:27][CH2:26]4)[cH:21]2)[CH2:14][CH2:15]1.[ClH:33].[N:1]1([C:6](=[O:7])[Cl:8])[CH2:2][CH2:3][CH2:4][CH2:5]1>>[N:1]1([C:6](=[O:7])[N:28]2[CH2:27][CH2:26][c:25]3[cH:24][cH:23][c:22](-[c:20]4[n:19][c:18]([NH2:32])[n:17][c:16]([N:13]5[CH2:12][CH2:11][N:10]([CH3:9])[CH2:15][CH2:14]5)[cH:21]4)[cH:31][c:30]3[CH2:29]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 709371-Pyrrolidinecarbonyl chloride

HCID 497794384-(4-Methylpiperazin-1-yl)-6-(1,2,3,4-tetrahydroisoquinolin-7-yl)pyrimidin-2-amine

생성물 1

HCID 497795154-(4-Methylpiperazin-1-yl)-6-[2-(pyrrolidin-1-ylcarbonyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyrimidin-2-amine

출처 및 근거

ORD 기록: ord-c45d1071da094e009f1fe6b92356176b
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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