Dichloromethane → 5-Fluoro-2-(3-pyrrolidin-1-ylmethyl-benzo[d]isoxazol-6-yloxy)-benzonitrile

반응식

[Br:1][CH2:2][c:3]1[n:4][o:5][c:6]2[c:7]1[cH:8][cH:9][c:10]([O:12][c:13]1[c:14]([C:15]#[N:16])[cH:17][c:18]([F:21])[cH:19][cH:20]1)[cH:11]2.[CH2:22]1[CH2:23][CH2:24][NH:25][CH2:26]1.[Cl:27][CH2:28][Cl:29]>>[CH2:2]([c:3]1[n:4][o:5][c:6]2[c:7]1[cH:8][cH:9][c:10]([O:12][c:13]1[c:14]([C:15]#[N:16])[cH:17][c:18]([F:21])[cH:19][cH:20]1)[cH:11]2)[N:25]1[CH2:24][CH2:23][CH2:22][CH2:26]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 31268Pyrrolidine

HCID 674092672-(3-Bromomethylbenzo[d]isoxazol-6-yloxy)-5-fluorobenzonitrile

생성물 1

HCID 674101705-Fluoro-2-(3-pyrrolidin-1-ylmethyl-benzo[d]isoxazol-6-yloxy)-benzonitrile

출처 및 근거

ORD 기록: ord-8055a8470301417698437f38d00a3574
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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