(4-Methoxyphenyl)boronic acid → HCID 86649261, 화합물

HRID 80456

반응식

HRID 80456 반응식
Br[C:2]1[S:6][C:5]([N:7]2[CH2:15][CH:14]3[CH2:16][N:10]4[CH2:11][CH:12]([CH2:17][CH:8]2[CH2:9]4)[CH2:13]3)=[N:4][CH:3]=1.[CH3:18][O:19][C:20]1[CH:25]=[CH:24][C:23](B(O)O)=[CH:22][CH:21]=1>>[CH3:18][O:19][C:20]1[CH:25]=[CH:24][C:23]([C:2]2[S:6][C:5]([N:7]3[CH2:15][CH:14]4[CH2:16][N:10]5[CH2:11][CH:12]([CH2:17][CH:8]3[CH2:9]5)[CH2:13]4)=[N:4][CH:3]=2)=[CH:22][CH:21]=1

참가 물질

3

반응물 2

HCID 201262(4-Methoxyphenyl)boronic acidHCID 866492624-(5-Bromo-1,3-thiazol-2-yl)-1,4-diazatricyclo[4.3.1.13,8]undecane

생성물 1

HCID 86649261HCID 86649261, 화합물

실험 절차

The title compound was prepared from the product of Example 105A and 4-methoxyphenylboronic acid according to General Method C: 1H NMR (500 MHz, CDCl3) δ ppm 7.35 (d, 2 H), 7.28 (s, 1 H), 6.88 (d, 2 H), 4.75-4.71 (m, 1 H), 3.64-3.59 (q, 2 H), 3.48-3.40 (q, 2 H), 3.08-3.05 (m, 4 H), 2.29-2.18 (m, 3 H), 1.88-1.80 (m, 3 H); LC-MS Method D (ESI+) m/z 342.0 (M+H)+, retention time 1.44 minutes.

출처 및 근거

ORD 기록
ord-75e1bac8b619483ebd476d563ce6b07e
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846661B2

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