Acetic Acid → 9-fluoro-6-(1-hydroxy-1-methylethyl)benzo[c]-1,6-naphthyridin-1(2H)-one

반응식

[BrH:25].[CH2:1]([CH2:2][CH2:3][CH3:4])[O:5][c:6]1[c:7]2[c:8]3[c:9]([c:10]([C:16]([CH3:17])([CH3:18])[OH:19])[n:11][c:12]2[cH:13][cH:14][n:15]1)[cH:20][cH:21][c:22]([F:24])[cH:23]3.[CH3:26][C:27](=[O:28])[OH:29]>>[O:5]=[c:6]1[c:7]2[c:8]3[c:9]([c:10]([C:16]([CH3:17])([CH3:18])[OH:19])[n:11][c:12]2[cH:13][cH:14][nH:15]1)[cH:20][cH:21][c:22]([F:24])[cH:23]3

참가 물질

반응물 3

HCID 176Acetic Acid

HCID 260Hydrogen Bromide

HCID 593756702-(1-Butoxy-9-fluorobenzo[c]-1,6-naphthyridin-6-yl)propan-2-ol

생성물 1

HCID 593756799-fluoro-6-(1-hydroxy-1-methylethyl)benzo[c]-1,6-naphthyridin-1(2H)-one

출처 및 근거

ORD 기록: ord-997f125fd308428795717a0a503589ca
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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