Dimethylformamide → 4-amino-5-(4-amino-3-fluorophenyl)-N-(2,2,2-trifluoroethyl)pyrrolo[2,1-f][1,2,4]triazine-6-carboxamide

HRID 806970노트

반응식

[CH3:28][N:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1.[F:22][C:23]([CH2:24][NH2:25])([F:26])[F:27].[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8](-[c:14]1[cH:15][c:16]([F:21])[c:17]([NH2:20])[cH:18][cH:19]1)[c:9]([C:11](=[O:12])[OH:13])[cH:10]2.[O:35]=[CH:36][N:37]([CH3:38])[CH3:39]>>[NH2:1][c:2]1[n:3][cH:4][n:5][n:6]2[c:7]1[c:8](-[c:14]1[cH:15][c:16]([F:21])[c:17]([NH2:20])[cH:18][cH:19]1)[c:9]([C:11](=[O:13])[NH:25][CH2:24][C:23]([F:22])([F:26])[F:27])[cH:10]2