Hydrochloric Acid → Piperidin-4-yl 2-(3,3-difluorocyclopentyl)-2-hydroxy-2-phenylacetate

반응식

[CH3:32][OH:33].[ClH:34].[F:1][C:2]1([F:31])[CH2:3][CH:4]([C:7]([C:8](=[O:9])[O:10][CH:11]2[CH2:12][CH2:13][N:14]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:15][CH2:16]2)([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[OH:30])[CH2:5][CH2:6]1>>[F:1][C:2]1([F:31])[CH2:3][CH:4]([C:7]([C:8](=[O:9])[O:10][CH:11]2[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]2)([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[OH:30])[CH2:5][CH2:6]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 887Methanol

HCID 22594546Tert-butyl 4-[2-(3,3-difluorocyclopentyl)-2-hydroxy-2-phenylacetyl]oxypiperidine-1-carboxylate

생성물 1

HCID 22594410Piperidin-4-yl 2-(3,3-difluorocyclopentyl)-2-hydroxy-2-phenylacetate

출처 및 근거

ORD 기록: ord-961b29f1ee0a4a4a9924c3fdee92026c
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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