Dimethylformamide → 4-[4-[1-[2-(azetidin-1-yl)ethyl]-4-(2,2,2-trifluoroethyl)imidazol-2-yl]piperidin-1-yl]-5-(trifluoromethyl)-6,8-dihydro-5H-pyrido[2,3-d]pyrimidin-7-one

반응식

[CH2:44]1[CH2:45][NH:46][CH2:47]1.[CH3:1][S:2]([O:3][CH2:6][CH2:7][n:8]1[c:9]([CH:18]2[CH2:19][CH2:20][N:21]([c:24]3[c:25]4[c:26]([n:27][cH:28][n:29]3)[NH:30][C:31](=[O:38])[CH2:32][CH:33]4[C:34]([F:35])([F:36])[F:37])[CH2:22][CH2:23]2)[n:10][c:11]([CH2:13][C:14]([F:15])([F:16])[F:17])[cH:12]1)(=[O:4])=[O:5].[CH3:39][N:40]([CH3:41])[CH:42]=[O:43].[CH3:48][CH2:49][O:50][C:51](=[O:52])[CH3:53]>>[CH2:6]([CH2:7][n:8]1[c:9]([CH:18]2[CH2:19][CH2:20][N:21]([c:24]3[c:25]4[c:26]([n:27][cH:28][n:29]3)[NH:30][C:31](=[O:38])[CH2:32][CH:33]4[C:34]([F:35])([F:36])[F:37])[CH2:22][CH2:23]2)[n:10][c:11]([CH2:13][C:14]([F:15])([F:16])[F:17])[cH:12]1)[N:46]1[CH2:45][CH2:44][CH2:47]1