Acetonitrile → Ethyl 5-[9-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl]pentanoate

반응식

[Br:38][CH2:39][CH2:40][CH2:41][CH2:42][C:43](=[O:44])[O:45][CH2:46][CH3:47].[CH3:1][CH:2]([CH3:3])[O:4][c:5]1[c:6]([C:7]#[N:8])[cH:9][c:10](-[c:13]2[n:14][c:15](-[c:18]3[cH:19][cH:20][cH:21][c:22]4[c:28]3[O:27][CH2:26][CH2:25][NH:24][CH2:23]4)[n:16][o:17]2)[cH:11][cH:12]1.[CH3:48][C:49]#[N:50].[CH:29]([N:30]([CH2:31][CH3:32])[CH:33]([CH3:34])[CH3:35])([CH3:36])[CH3:37]>>[CH3:1][CH:2]([CH3:3])[O:4][c:5]1[c:6]([C:7]#[N:8])[cH:9][c:10](-[c:13]2[n:14][c:15](-[c:18]3[cH:19][cH:20][cH:21][c:22]4[c:28]3[O:27][CH2:26][CH2:25][N:24]([CH2:39][CH2:40][CH2:41][CH2:42][C:43](=[O:44])[O:45][CH2:46][CH3:47])[CH2:23]4)[n:16][o:17]2)[cH:11][cH:12]1