Hydrochloric Acid → HCID 178478314, 화합물

HRID 82566

반응식

HRID 82566 반응식
CS[C:3]1[NH:11][C:6]2=[N:7][CH:8]=[CH:9][CH:10]=[C:5]2[N:4]=1.[ClH:12]>>[Cl:12][C:3]1[NH:11][C:6]2=[N:7][CH:8]=[CH:9][CH:10]=[C:5]2[N:4]=1

참가 물질

3

반응물 2

HCID 313Hydrochloric AcidHCID 178503348HCID 178503348, 화합물

생성물 1

HCID 178478314HCID 178478314, 화합물

반응 조건

온도
0 °C

실험 절차

2-(Methylthio)-3H-imidazo[4,5-b]pyridine (3.5 g) was dissolved in conc. HCl (10 mL), and then the mixture was cooled to 0° C. Chlorine gas was bubbled through the mixture for 2 h in iced bath. The mixture was poured onto ice, and neutralized to pH 7 with aqueous ammonium solution. The precipitate was collected by filtration to give the title compound as white crystals (1.0 g).

후처리

  1. customChlorine gas was bubbled through the mixture for 2 h in iced bath
  2. additionThe mixture was poured onto ice
  3. filtrationThe precipitate was collected by filtration

출처 및 근거

ORD 기록
ord-0d86605a2fca46b7baa041ea345da716
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846713B2

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