Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzene → 2-(4-Methoxymethoxyphenyl)-5,5-dimethyl-1,3-dioxane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzene | HCID 241 | — |
| 반응물 | Neopentyl glycol | HCID 31344 | — |
| 반응물 | 4-(Methoxymethoxy)benzaldehyde | HCID 250074 | — |
| 반응물 | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 2-(4-Methoxymethoxyphenyl)-5,5-dimethyl-1,3-dioxane | HCID 9942983 | — |
반응 단계
A solution of 4-methoxymethoxybenzaldehyde, neopentyl glycol (10.3 g, 98.9 mmol), pyridinium para-toluenesulfonate (1.0 g, 3.98 mmol), and benzene (500 ml) was refluxed with azeotropic removal of water for several hours, under argon. The cooled reaction mixture was quenched with 2 ml of triethylamine, and concentrated on rotary evaporator. The product was chromatographed (silica gel, 5% ethyl acetate in hexanes), yielding about 14.83 g of the product.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846735B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-ffbd58b7353f45b0ba190e0fd9c8f074 |
| 출처 메모 | uspto-grants-2014_09 |