Hydrochloric Acid → 5-(3-Benzyl-pyrrolidine-3-carbonyl)-1H-indole-3-carbonitrile

반응식

[C:2]([O:3][C:4](=[O:5])[N:9]1[CH2:10][C:11]([C:14](=[O:15])[c:16]2[cH:17][c:18]3[c:19]([C:25]#[N:26])[cH:20][nH:21][c:22]3[cH:23][cH:24]2)([CH2:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:12][CH2:13]1)([CH3:6])([CH3:7])[CH3:8].[CH3:34][OH:35].[ClH:1]>>[NH:9]1[CH2:10][C:11]([C:14](=[O:15])[c:16]2[cH:17][c:18]3[c:19]([C:25]#[N:26])[cH:20][nH:21][c:22]3[cH:23][cH:24]2)([CH2:27][c:28]2[cH:29][cH:30][cH:31][cH:32][cH:33]2)[CH2:12][CH2:13]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 887Methanol

HCID 666876893-benzyl-3-(3-cyano-1H-indole-5-carbonyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

생성물 1

HCID 597447375-(3-Benzyl-pyrrolidine-3-carbonyl)-1H-indole-3-carbonitrile

출처 및 근거

ORD 기록: ord-7bb530fe10db408bbc3fbb78bcb91f17
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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