Hydrochloric Acid → (6-Bromopyridin-3-yl)[4-(3-cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazin-1-yl]methanone

반응식

[Br:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1.[CH:12]1([c:15]2[c:16]([N:25]3[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]3)[n:17][cH:18][c:19]([C:21]([F:22])([F:23])[F:24])[cH:20]2)[CH2:13][CH2:14]1.[ClH:11]>>[Br:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:8])[N:28]2[CH2:27][CH2:26][N:25]([c:16]3[c:15]([CH:12]4[CH2:13][CH2:14]4)[cH:20][c:19]([C:21]([F:22])([F:23])[F:24])[cH:18][n:17]3)[CH2:30][CH2:29]2)[cH:9][cH:10]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 2389326-Bromonicotinic acid

HCID 584847721-(3-Cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazine

생성물 1

HCID 58484523(6-Bromopyridin-3-yl)[4-(3-cyclopropyl-5-trifluoromethylpyridin-2-yl)piperazin-1-yl]methanone

출처 및 근거

ORD 기록: ord-794d13b2b7664c5ba3d90270a9d90d01
출처 데이터셋: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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