Acetic Acid → N5-(3-(1H-pyrazolo[3,4-d]pyrimidin-4-yl)pyridin-2-yl)-6-methyl-N1-(3-(trifluoromethyl)phenyl)isoquinoline-1,5-diamine

HRID 835736

반응식

[C:58]([OH:59])(=[O:60])[CH3:61].[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:17][c:18]1[c:19]([NH2:39])[c:20]2[cH:21][cH:22][n:23][c:24]([NH:28][c:29]3[cH:30][c:31]([C:35]([F:36])([F:37])[F:38])[cH:32][cH:33][cH:34]3)[c:25]2[cH:26][cH:27]1.[CH3:40][Si:41]([N-:42][Si:43]([CH3:44])([CH3:45])[CH3:46])([CH3:47])[CH3:48].[CH3:51][OH:52].[CH3:62][OH:63].[F:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[nH:14][n:15][cH:16]2.[Li+:49].[NH3:50]>>[c:2]1([NH:39][c:19]2[c:18]([CH3:17])[cH:27][cH:26][c:25]3[c:20]2[cH:21][cH:22][n:23][c:24]3[NH:28][c:29]2[cH:30][c:31]([C:35]([F:36])([F:37])[F:38])[cH:32][cH:33][cH:34]2)[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[c:9]2[c:10]([n:11][cH:12][n:13]1)[nH:14][n:15][cH:16]2