Water → N-tert-butyl-5-(5-(cyclopropylcarbamoyl)-2-methylphenyl)thiophene-2-carboxamide

HRID 836078

반응식

[Br:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][C:10]([CH3:11])([CH3:12])[CH3:13])[s:6]1.[CH2:38]1[O:39][CH2:40][CH2:41][O:42][CH2:43]1.[CH3:44][CH2:45][O:46][C:47]([CH3:48])=[O:49].[CH:14]1([NH:17][C:18]([c:19]2[cH:20][c:21]([B:26]3[O:27][C:28]([CH3:29])([CH3:30])[C:31]([CH3:32])([CH3:33])[O:34]3)[c:22]([CH3:25])[cH:23][cH:24]2)=[O:35])[CH2:15][CH2:16]1.[Cs+:37].[F-:36].[OH2:127].[cH:50]1[cH:51][cH:52][c:53]([P:54]([Pd:55]([P:56]([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)([P:75]([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[P:94]([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)([c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)[cH:125][cH:126]1>>[c:2]1(-[c:21]2[cH:20][c:19]([C:18]([NH:17][CH:14]3[CH2:15][CH2:16]3)=[O:35])[cH:24][cH:23][c:22]2[CH3:25])[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][C:10]([CH3:11])([CH3:12])[CH3:13])[s:6]1