Hydrogen Bromide → 1-Bromo-3,7-dimethyloctane

HRID 84062

반응식

HRID 84062 반응식
S(=O)(=O)(O)O.[CH3:6][CH:7]([CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH2:8][CH2:9]O.[BrH:17]>>[CH3:6][CH:7]([CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH2:8][CH2:9][Br:17]

참가 물질

4

반응물 3

HCID 260Hydrogen BromideHCID 1118Sulfuric AcidHCID 77923,7-Dimethyl-1-octanol

생성물 1

HCID 1379141-Bromo-3,7-dimethyloctane수율 82.1%

실험 절차

48% HBr (200 ml) and concentrated sulfuric acid (0.46 ml) were added to 3,7-dimethyl-1-octanol (21.0 g, 157.9 mmol), and the mixture was heated overnight. After allowing to cool to room temperature, and the mixture was extracted with hexane. The organic layer was washed with 5% aqueous sodium hydrogen carbonate solution and saturated brine, dried and concentrated to give the title compound (28.7 g, 82.1%).

후처리

  1. temperaturethe mixture was heated overnight
  2. extractionthe mixture was extracted with hexane
  3. washThe organic layer was washed with 5% aqueous sodium hydrogen carbonate solution and saturated brine
  4. customdried
  5. concentrationconcentrated

출처 및 근거

ORD 기록
ord-68ffd444f96c4333a3dda341ab53f8fc
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846885B2

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