Hydrogen Bromide → 1-Bromo-3,7-dimethyloctane

반응식

S(=O)(=O)(O)O.[CH3:6][CH:7]([CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH2:8][CH2:9]O.[BrH:17]>>[CH3:6][CH:7]([CH2:11][CH2:12][CH2:13][CH:14]([CH3:16])[CH3:15])[CH2:8][CH2:9][Br:17]

참가 물질

반응물 3

HCID 260Hydrogen Bromide

HCID 1118Sulfuric Acid

HCID 77923,7-Dimethyl-1-octanol

생성물 1

HCID 1379141-Bromo-3,7-dimethyloctane수율 82.1%

실험 절차

48% HBr (200 ml) and concentrated sulfuric acid (0.46 ml) were added to 3,7-dimethyl-1-octanol (21.0 g, 157.9 mmol), and the mixture was heated overnight. After allowing to cool to room temperature, and the mixture was extracted with hexane. The organic layer was washed with 5% aqueous sodium hydrogen carbonate solution and saturated brine, dried and concentrated to give the title compound (28.7 g, 82.1%).

후처리

temperaturethe mixture was heated overnight
extractionthe mixture was extracted with hexane
washThe organic layer was washed with 5% aqueous sodium hydrogen carbonate solution and saturated brine
customdried
concentrationconcentrated

출처 및 근거

ORD 기록: ord-68ffd444f96c4333a3dda341ab53f8fc
출처 데이터셋: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08846885B2

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