Hydrochloric Acid → HCID 22617787, 화합물

HRID 842073노트

반응식

HRID 842073 반응식
[CH2:1]([N:8]([CH2:29][CH3:30])[C:9](=[O:28])[CH2:10][N:11]1[C:19](=[O:20])[N:18]([CH3:21])[C:17]2[C:12]1=[N:13][C:14]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)=[N:15][CH:16]=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:31]>C(O)C>[ClH:31].[CH2:1]([N:8]([CH2:29][CH3:30])[C:9](=[O:28])[CH2:10][N:11]1[C:19](=[O:20])[N:18]([CH3:21])[C:17]2[C:12]1=[N:13][C:14]([C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)=[N:15][CH:16]=2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 6433109Emapunil

생성물 1

HCID 22617787HCID 22617787, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매2회

실험 절차

To a mixture of N-benzyl-N-ethyl-7,8-dihydro-7-methyl-8-oxo-2-phenyl-9H-purin-9-acetamide (0.8 g) obtained in Example 146 and ethanol (15 ml) is added 30% hydrochloric acid in ethanol (15 ml) at 80° C., and the mixture is stirred for 30 minutes. The reaction mixture is cooled to room temperature, and the precipitates are collected by filtration, and washed with ethanol to give the desired compound (0.85 g).

후처리

  1. filtrationthe precipitates are collected by filtration
  2. washwashed with ethanol

출처 및 근거

ORD 기록
ord-88a8a3c6fdba4222a3d86421b74442b2
출처 데이터셋
uspto-grants-2002_04
특허 번호
US06372740B1

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