Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → Diacetone-D-glucose
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Alpha-D-Glucose | HCID 79025 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | Diacetone-D-glucose | HCID 7067560 | 112.5% |
반응 단계
Sulfuric acid (40 ml) is added dropwise to a solution of α-D-glucose (41) (50 g, 0,28 mol) in acetone (1 l) at 0° C. The reaction mixture is stirred for 24 h and then it is neutralized using sodium hydroxide (6 M). The acetone is evaporated and the aqueous layer is extracted with chloroform (X2). The chloroform is dried (MgSO4) filtered and evaporated. Crystallization from cyclohexane yielded the di-isopropylidene glucose (42) (41 g, 57%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06376657B1 |
| 출처 데이터셋 | uspto-grants-2002_04 |
| ORD ID | ord-80b91a09cd0a4ad6b1d6e94c624dd2c4 |
| 출처 메모 | uspto-grants-2002_04 |