Sodium Hydroxide → 2,4-Dichloro-5-methoxyaniline

HRID 846502노트

반응식

HRID 846502 반응식
CC([NH:4][C:5]1[C:10]([Cl:11])=[CH:9][C:8]([Cl:12])=[C:7]([O:13][CH3:14])[CH:6]=1)=O.[OH-].[Na+]>O.C(O)C>[Cl:11][C:10]1[CH:9]=[C:8]([Cl:12])[C:7]([O:13][CH3:14])=[CH:6][C:5]=1[NH2:4]

참가 물질

5

반응물 2

HCID 14798Sodium HydroxideHCID 14593783N-(2,4-Dichloro-5-methoxyphenyl)acetamide

생성물 1

HCID 14766362,4-Dichloro-5-methoxyaniline수율 54.3%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매

실험 절차

In the manner of Example 2, Step C, the reaction of 37.4 g (0.16 mole) of 2,4-dichloro-5-methoxyacetanilide with 12.8 g (0.32 mole) of sodium hydroxide in 30 mL of water and 30 mL of ethanol produced 16.7 g of 2,4-dichloro-5-methoxyaniline.

출처 및 근거

ORD 기록
ord-b63b709da36d4403aeed1e3a384f5dcc
출처 데이터셋
uspto-grants-1992_08
특허 번호
US05136868

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