Morpholine → HCID 19883113, 화합물
반응식
[F:1][C:2]1[N:7]=[C:6]([S:8](Cl)(=[O:10])=[O:9])[CH:5]=[CH:4][CH:3]=1.[NH:12]1[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1>C(Cl)(Cl)Cl>[N:12]1([S:8]([C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([F:1])[N:7]=2)(=[O:10])=[O:9])[CH2:17][CH2:16][O:15][CH2:14][CH2:13]1참가 물질
4
실험 절차
To a solution of 6-fluoropyridine-2-sulphonyl chloride (1.96 g) in chloroform (40 cm3) at 0° C. was added a solution of morpholine (1.74 g) in chloroform (20 cm3). The reaction was quenched in water (100 cm3) and the product extracted into chloroform (3×50 cm3). The combined organic layers were washed with water, dried over anhydrous magnesium sulphate and the solvent evaporated under reduced pressure to give the title compound which was used without further purification.
후처리
- customThe reaction was quenched in water (100 cm3)
- extractionthe product extracted into chloroform (3×50 cm3)
- washThe combined organic layers were washed with water
- dry with materialdried over anhydrous magnesium sulphate
- customthe solvent evaporated under reduced pressure
출처 및 근거
- ORD 기록
- ord-ef7be755cc6f4a20b3d82e71de298a66
- 출처 데이터셋
- uspto-grants-1992_08
- 특허 번호
- US05137886
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