Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Propanediamine → N-(3-aminopropyl)pyrimidin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Propanediamine | HCID 428 | — |
| 반응물 | 2-Bromopyrimidine | HCID 78345 | — |
| 반응물 | Sodium ethoxide | HCID 2723922 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | N-(3-aminopropyl)pyrimidin-2-amine | HCID 14397405 | — |
반응 단계
Reaction of 2-bromopyrimidine with 1,3-diaminopropane in ethanol containing sodium ethoxide gives 2-(3-aminopropylamino)pyrimidine which on reaction with methyl isothiocyanate results in the production of N-methyl-N'-[3-(2-pyrimidylamino)propyl]thiourea.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04293697 |
| 출처 데이터셋 | uspto-grants-1981_10 |
| ORD ID | ord-b51f003eb8ef4c75a073dbf28f2aea17 |
| 출처 메모 | uspto-grants-1981_10 |