Disodium → Tazasubrate

HRID 848110

반응식

HRID 848110 반응식
Cl[C:2]1[S:3][C:4]2[CH:10]=[C:9]([O:11][CH2:12][CH3:13])[CH:8]=[CH:7][C:5]=2[N:6]=1.[Na][Na].[SH:16][C:17]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)([CH3:21])[C:18]([OH:20])=[O:19]>C(O)CCC>[CH2:12]([O:11][C:9]1[CH:8]=[CH:7][C:5]2[N:6]=[C:2]([S:16][C:17]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)([CH3:21])[C:18]([OH:20])=[O:19])[S:3][C:4]=2[CH:10]=1)[CH3:13]

참가 물질

5

반응물 3

HCID 141233DisodiumHCID 3500152-Chloro-6-ethoxybenzo[d]thiazoleHCID 15910000alpha-Mercapto-alpha-methylbenzeneacetic acid

생성물 1

HCID 174749Tazasubrate

시약·촉매·용매 1

HCID 2631-Butanol용매

실험 절차

A mixture of 21.4 g of 2-chloro-6-ethoxybenzothiazole, 22.6 g of the disodium salt of 2-mercapto-2-phenylpropionic acid and 200 ml of n-butanol is boiled for 4 hours and is evaporated and worked up in the customary manner to give 2-(6-ethoxybenzothiazol-2-ylthio)-2-phenylpropionic acid, m.p. 152°-153°.

후처리

  1. customis evaporated

출처 및 근거

ORD 기록
ord-bd71f7a719a7494a83737c39639230c7
출처 데이터셋
uspto-grants-1981_10
특허 번호
US04294839

연결된 노트

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