Acetic Anhydride → HCID 20248673, 화합물

HRID 848394노트

반응식

HRID 848394 반응식
S([O-])([O-])=O.[Na+].[Na+].S(O)(O)(=O)=O.[S:12]([NH:16][CH2:17][CH2:18][NH:19][C:20]1[CH:25]=[CH:24][C:23]([NH2:26])=[CH:22][CH:21]=1)([CH3:15])(=[O:14])=[O:13].[C:27](OC(=O)C)(=[O:29])[CH3:28]>O>[C:27]([NH:26][C:23]1[CH:24]=[CH:25][C:20]([NH:19][CH2:18][CH2:17][NH:16][S:12]([CH3:15])(=[O:13])=[O:14])=[CH:21][CH:22]=1)(=[O:29])[CH3:28]

참가 물질

5

반응물 3

HCID 7918Acetic AnhydrideHCID 24437Sodium SulfiteHCID 458930N-[2-(4-aminoanilino)ethyl]methanesulfonamide; sulfuric acid

생성물 1

HCID 20248673HCID 20248673, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

0.2 mol (25.2 g) of sodium sulphite is added, at ambient temperature, to a solution of 0.1 mol (32.7 g) of N-(β-mesylaminoethyl)-para-phenylenediamine sulphate in 150 ml of water, and 0.13 mol (13.17 g) of acetic anhydride is added gradually, whilst stirring. When the addition is complete, stirring is continued for one hour and the expected acetylated derivative which has precipitated in crystalline form is then filtered off. The product is drained, washed with water and dried in vacuo. After recrystallisation from alcohol and drying in vacuo, it melts at 130° C.

후처리

  1. additionis added gradually
  2. additionWhen the addition
  3. stirringstirring
  4. customthe expected acetylated derivative which has precipitated in crystalline form
  5. filtrationis then filtered off
  6. washwashed with water
  7. customdried in vacuo
  8. customAfter recrystallisation from alcohol
  9. customdrying in vacuo, it melts at 130° C.

출처 및 근거

ORD 기록
ord-eeefe92c406c44e98bdbe8f2962e95e7
출처 데이터셋
uspto-grants-1981_10
특허 번호
US04295848

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