Ammonium Acetate → 3-Amino-1-(4-chlorophenyl)-1,2-dihydroquinoxalin-2-one
반응식
C([O-])(=O)C.[NH4+:5].[Cl:6][C:7]1[CH:12]=[CH:11][C:10]([N:13]2[C:22]3[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=3)[N:16]=[C:15](OCC)[C:14]2=[O:26])=[CH:9][CH:8]=1>O>[NH2:5][C:15]1[C:14](=[O:26])[N:13]([C:10]2[CH:11]=[CH:12][C:7]([Cl:6])=[CH:8][CH:9]=2)[C:22]2[C:17]([N:16]=1)=[CH:18][CH:19]=[CH:20][CH:21]=2참가 물질
4
실험 절차
To a melt of ammonium acetate (62 g) at 160° C. was added 1-(4-chlorophenyl)-1,2-dihydro-3-ethoxyquinoxalin-2-one (8.8 g) and the temperature was then raised during 5 minutes to 200° C. and maintained at this level for 15 minutes. The melt was cooled, water was added, and the product was filtered off. Crystallisation from ethanol gave the title compound (5.6 g) mp 254°-255° C.
후처리
- temperaturethe temperature was then raised during 5 minutes to 200° C.
- temperaturemaintained at this level for 15 minutes
- temperatureThe melt was cooled
- filtrationthe product was filtered off
- customCrystallisation from ethanol
출처 및 근거
- ORD 기록
- ord-6a044e9c5d98424e8147b462d0d79187
- 출처 데이터셋
- uspto-grants-1981_10
- 특허 번호
- US04296114
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