Hydrochloric Acid → 1-Aminocyclopentane-1-carboxamide hydrochloride

HRID 84919노트

반응식

HRID 84919 반응식
[C:1]([C:4]1([NH:9]C(=O)OC(C)(C)C)[CH2:8][CH2:7][CH2:6][CH2:5]1)(=[O:3])[NH2:2].[ClH:17]>O1CCOCC1>[ClH:17].[NH2:9][C:4]1([C:1]([NH2:2])=[O:3])[CH2:8][CH2:7][CH2:6][CH2:5]1

참가 물질

4

반응물 2

HCID 313Hydrochloric Acid2회HCID 106808671-Tert-butoxycarbonylamino-1-cyclopentanecarboxamide

생성물 1

HCID 545931881-Aminocyclopentane-1-carboxamide hydrochloride

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

A solution of tert-butyl 1-carbamoylcyclopentylcarbamate (305 mg, 1.33 mmol) in 4N HCl in dioxane (5 mL) and aq. 6N HCl (3 mL) was stirred at room temperature for 3 h. It was then concentrated in vacuo to give 1-aminocyclopentanecarboxamide hydrochloride as a solid (214 mg).

후처리

  1. concentrationIt was then concentrated in vacuo

출처 및 근거

ORD 기록
ord-a43fbb7c1ba4499c8a9ed229a92ef8a5
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846928B2

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