Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
O-Benzylhydroxylamine → 2-(Benzyloxyaminomethyl)-4-methylpentanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | O-Benzylhydroxylamine | HCID 102313 | — |
| 반응물 | 4-Methyl-2-methylene valeric acid | HCID 168659 | — |
| 생성물 | 2-(Benzyloxyaminomethyl)-4-methylpentanoic acid | HCID 19367517 | — |
반응 단계
A solution of 4-methyl-2-methylenepentanoic acid (3.5 g) and O-benzylhydroxylamine were heated at 1200 for 8 h. The reaction mixture was then partitioned between 50 mL of 1.0 N NaOH and 50 mL of diethyl ether. The aqueous portion was separated, acidified to pH 3 with 10% HCl and washed with 50 mL of ether. Ion exchange chromatography (Dowex--50W) eluting with 20% pyridine/water gave 2-(benzyloxyaminomethyl)-4-methylpentanoic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06013792 |
| 출처 데이터셋 | uspto-grants-2000_01 |
| ORD ID | ord-9abea112611e46cc9a321cea3918af3b |
| 출처 메모 | uspto-grants-2000_01 |