Sucrose → (2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;prop-2-enoate

HRID 850693

반응식

HRID 850693 반응식
[CH2:1]([OH:23])[C@H:2]1[O:7][C@H:6]([O:8][C@:9]2([CH2:18][OH:19])[O:13][C@H:12]([CH2:14][OH:15])[C@@H:11]([OH:16])[C@@H:10]2[OH:17])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@@H:3]1[OH:22].COC1C=CC(O)=CC=1.[C:33]([O:37]CC1OC1)(=[O:36])[CH:34]=[CH2:35].[Al]>P([O-])([O-])([O-])=O>[CH2:1]([OH:23])[C@H:2]1[O:7][C@H:6]([O:8][C@:9]2([CH2:18][OH:19])[O:13][C@H:12]([CH2:14][OH:15])[C@@H:11]([OH:16])[C@@H:10]2[OH:17])[C@H:5]([OH:20])[C@@H:4]([OH:21])[C@@H:3]1[OH:22].[C:33]([O-:37])(=[O:36])[CH:34]=[CH2:35]

참가 물질

6

반응물 4

HCID 5988Sucrose2회HCID 7836Glycidyl acrylate2회HCID 90154-MethoxyphenolHCID 5359268Aluminum

생성물 1

HCID 131721615(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;prop-2-enoate

시약·촉매·용매 1

HCID 1061Phosphate용매

실험 절차

Four batches of sucrose acrylate monomers were prepared. For each batch, 10 g of sucrose, 1.9 g of TAB (99%), and a small amount of p-methoxyphenol, which was used as a polymerization inhibitor, were dissolved in 20 ml phosphate buffered aqueous solution (pH 7.2, 0.05 M) in a 200 ml Erlenmeyer flask equipped with magnetic stirrer. The TAB was used as a phase transfer catalyst. Glycidyl acrylate (GA) (Lancaster Synthesis, Inc.; Windham, N.H.) was added to each batch to make sucrose:GA ratios of 1:4, 1:1.5, 1:1:5, and 1:8. The reaction was performed at room temperature with continuous stirring and the flasks were covered with aluminum foil to avoid the light.

후처리

  1. customequipped with magnetic stirrer
  2. customwas performed at room temperature

출처 및 근거

ORD 기록
ord-00c5568940204401afab0faf8b41193f
출처 데이터셋
uspto-grants-2000_01
특허 번호
US06018033

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