Acetic acid, bromo-, propyl ester → 10-bromo-2-n-propoxycarbonylmethyloxy-5-(3-pyridylmethyl)-4H-pyrido [3,2,1-jk]carbazole-4-one

HRID 850739

반응식

HRID 850739 반응식
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]3[CH:18]=[C:17]([CH2:19][C:20]4[CH:21]=[N:22][CH:23]=[CH:24][CH:25]=4)[C:16](=[O:26])[C:8]4[CH:9]=[C:10]([OH:15])[CH:11]=[C:12]([C:13]=2[CH:14]=1)[C:7]3=4.Br[CH2:28][C:29]([O:31][CH2:32][CH2:33][CH3:34])=[O:30]>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]3[CH:18]=[C:17]([CH2:19][C:20]4[CH:21]=[N:22][CH:23]=[CH:24][CH:25]=4)[C:16](=[O:26])[C:8]4[CH:9]=[C:10]([O:15][CH2:28][C:29]([O:31][CH2:32][CH2:33][CH3:34])=[O:30])[CH:11]=[C:12]([C:13]=2[CH:14]=1)[C:7]3=4

참가 물질

3

반응물 2

HCID 141981Acetic acid, bromo-, propyl esterHCID 1588691010-bromo-2-hydroxy-5-(3-pyridylmethyl)-4H-pyrido[3,2,1-jk]carbazole-4-one

생성물 1

HCID 1588691410-bromo-2-n-propoxycarbonylmethyloxy-5-(3-pyridylmethyl)-4H-pyrido [3,2,1-jk]carbazole-4-one수율 55%

실험 절차

The procedure of Example 3 was repeated by using 10-bromo-2-hydroxy-5-(3-pyridylmethyl)-4H-pyrido[3,2,1-jk]carbazole-4-one (250 mg) and n-propyl bromoacetate (0.1 ml) to obtain the title compound (170 mg, 55%).

출처 및 근거

ORD 기록
ord-f19c4576aba94882bcb6692696660357
출처 데이터셋
uspto-grants-2000_01
특허 번호
US06018046

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