반응식
N1C2C=CC=CC=2NC=1.[NH2:10][C:11]1[C:19]([NH2:20])=[CH:18][CH:17]=[CH:16][C:12]=1[C:13]([OH:15])=[O:14].[CH:21]([C:23]1[CH:42]=[CH:41][CH:40]=[CH:39][C:24]=1[O:25][CH:26]1[CH2:31][CH2:30][N:29]([C:32]([O:34][C:35]([CH3:38])([CH3:37])[CH3:36])=[O:33])[CH2:28][CH2:27]1)=O>>[C:35]([O:34][C:32]([N:29]1[CH2:28][CH2:27][CH:26]([O:25][C:24]2[CH:39]=[CH:40][CH:41]=[CH:42][C:23]=2[C:21]2[NH:20][C:19]3[CH:18]=[CH:17][CH:16]=[C:12]([C:13]([OH:15])=[O:14])[C:11]=3[N:10]=2)[CH2:31][CH2:30]1)=[O:33])([CH3:38])([CH3:37])[CH3:36]참가 물질
4
실험 절차
The same general procedure outlined above for the preparation of benzimidazole derivatives was used, employing 2,3-diaminobenzoic acid 1 and tert-butyl 4-(2-formylphenoxy)piperidine-1-carboxylate 26 to produce 2-(2-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)phenyl)-1H-benzo[d]imidazole-4-carboxylic acid 27. MS (ESI) calcd for C24H27N3O5: 437.20; found: 438 [M+H].
출처 및 근거
- ORD 기록
- ord-eca130390ed14a34a525b6f814aea8f2
- 출처 데이터셋
- uspto-grants-2014_09
- 특허 번호
- US08846947B2
연결된 노트
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