Chloroacetone → HCID 13136937, 화합물

HRID 851204노트

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HRID 851204 반응식
[Cl:1][C:2]1[C:3]([CH3:17])=[CH:4][C:5]2[O:15][C:14](=[O:16])[C:9]3[CH2:10][NH:11][CH2:12][CH2:13][C:8]=3[C:6]=2[CH:7]=1.C(N(CC)CC)C.Cl[CH2:26][C:27](=[O:29])[CH3:28]>>[Cl:1][C:2]1[C:3]([CH3:17])=[CH:4][C:5]2[O:15][C:14](=[O:16])[C:9]3[CH2:10][N:11]([CH2:26][C:27](=[O:29])[CH3:28])[CH2:12][CH2:13][C:8]=3[C:6]=2[CH:7]=1

참가 물질

4

반응물 3

HCID 6571ChloroacetoneHCID 8471TriethylamineHCID 13136928HCID 13136928, 화합물

생성물 1

HCID 13136937HCID 13136937, 화합물수율 27.3%

실험 절차

Prepared by the method described for example 26 from 9-chloro-1,2,3,4-tetrahydro-8-methyl-5H-[1]benzopyrano[3,4-c]pyridin-5-one (1.6 g, 0.006 moles), triethylamine (1 ml, 0.007 moles) and 1-chloro-2-propanone (0.57 g, 0.006 moles). Recrystallization from isopropanol gave the product (0.5 g), mp 172°-175° C.

후처리

  1. customPrepared by the method
  2. customRecrystallization from isopropanol

출처 및 근거

ORD 기록
ord-1d18f9a586ad43b4ab6b0c337cf2e451
출처 데이터셋
uspto-grants-1983_05
특허 번호
US04382939

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