Sodium Hydroxide → 4-Hydroxyfentiazac

반응식

C([O:4][C:5]1[CH:10]=[CH:9][C:8]([C:11]2[S:12][C:13]([CH2:23][C:24]([OH:26])=[O:25])=[C:14]([C:16]3[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=3)[N:15]=2)=[CH:7][CH:6]=1)(=O)C.[OH-].[Na+]>>[Cl:22][C:19]1[CH:18]=[CH:17][C:16]([C:14]2[N:15]=[C:11]([C:8]3[CH:7]=[CH:6][C:5]([OH:4])=[CH:10][CH:9]=3)[S:12][C:13]=2[CH2:23][C:24]([OH:26])=[O:25])=[CH:21][CH:20]=1

참가 물질

반응물 2

HCID 14798Sodium Hydroxide

HCID 12940897HCID 12940897, 화합물

생성물 1

HCID 1289074-Hydroxyfentiazac

실험 절차

2-(4-Acetoxyphenyl)-4-(4-chlorophenyl)-thiazole-5-acetic acid (prepared according to Example 3) is hydrolysed using 2 N sodium hydroxide to give the title compound.

출처 및 근거

ORD 기록: ord-2975fa6a46b347ecaf9575ce39a7970b
출처 데이터셋: uspto-grants-1983_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04385059

반응 노트

불러오는 중…