1,2-Hydrazinedicarboxamide → 1-(3,5-Dioxo-1,2,4-triazolidin-4-yl-methyl)-1,3,3-trimethyl-5-(3,5-dioxo-1,2,4-triazolidin-4-yl)-cyclohexane

HRID 851793

반응식

HRID 851793 반응식
[NH2:1][CH2:2][C:3]1([CH3:12])[CH2:8][CH:7]([NH2:9])[CH2:6][C:5]([CH3:11])([CH3:10])[CH2:4]1.[C:13]([NH:16][NH:17][C:18](N)=[O:19])(N)=[O:14]>CN1CCCC1=O>[O:14]=[C:13]1[N:1]([CH2:2][C:3]2([CH3:12])[CH2:8][CH:7]([N:9]3[C:18](=[O:19])[NH:17][NH:16][C:13]3=[O:14])[CH2:6][C:5]([CH3:11])([CH3:10])[CH2:4]2)[C:18](=[O:19])[NH:17][NH:16]1

참가 물질

4

반응물 2

HCID 80391,2-HydrazinedicarboxamideHCID 17857Isophorone diamine

생성물 1

HCID 205012001-(3,5-Dioxo-1,2,4-triazolidin-4-yl-methyl)-1,3,3-trimethyl-5-(3,5-dioxo-1,2,4-triazolidin-4-yl)-cyclohexane

시약·촉매·용매 1

HCID 13387N-methyl-2-pyrrolidone용매

실험 절차

765 g of 1-aminomethyl-5-amino-1,3,3-trimethyl cyclohexane and 708 g of hydrazodicarbonamide are stirred in 1 liter of N-methyl pyrrolidone for 4 hours at 175° C., for 5 hours at 200° C. and for 15 hours at 220° C. The solvent is then distilled off in vacuo and the residue is dried in vacuo, giving 1473 g (97% of the theoretical) of 1-(3,5-dioxo-1,2,4-triazolidin-4-yl-methyl)-1,3,3-trimethyl-5-(3,5-dioxo-1,2,4-triazolidin-4-yl)-cyclohexane in the form of colourless crystals melting at 213 C. (decomposition).

후처리

  1. distillationThe solvent is then distilled off in vacuo
  2. customthe residue is dried in vacuo

출처 및 근거

ORD 기록
ord-49e66688c7f741a58513d0d398a2048b
출처 데이터셋
uspto-grants-1983_05
특허 번호
US04386213

연결된 노트

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