Toluene → HCID 54150769, 화합물

HRID 851814노트

반응식

HRID 851814 반응식
C1(S([CH2:10][CH2:11][CH2:12][CH:13]2[CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][C:14]2=O)(=O)=O)C=CC=CC=1.CCC([O-])(C)C.[Na+].C1(C)C=CC=CC=1>CS(C)=O>[C:13]12[CH2:12][CH2:11][CH:10]=[C:14]1[CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH:24]=2

참가 물질

5

반응물 3

HCID 1140TolueneHCID 2733478Sodium 2-methylbutan-2-olateHCID 205012032-[3-(Benzenesulfonyl)propyl]cyclododecan-1-one

생성물 1

HCID 54150769HCID 54150769, 화합물수율 76%

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매

실험 절차

18.2 g (0.05 mole) of 2-(3-phenylsulfonyl-prop-1-yl)-cyclododecanone, 33.0 g (0.30 mole) of sodium tert-pentoxide and 100 ml of toluene were subjected to the treatments described sub letter (a). After addition of 15 ml of DMSO, heating at 110° for 4 hours and final treatments as indicated hereinabove, there were isolated 7.75 g (76% yield) of the desired compound.

후처리

  1. temperatureheating at 110° for 4 hours

출처 및 근거

ORD 기록
ord-b0c9d227e12b48c1a1612dd3c3da023d
출처 데이터셋
uspto-grants-1983_05
특허 번호
US04386220

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