Ethanol → 2-(Butylsulfanyl)cyclopentan-1-one

HRID 851834노트

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HRID 851834 반응식
[Na].[CH2:2]([SH:6])[CH2:3][CH2:4][CH3:5].Cl[CH:8]1[CH2:12][CH2:11][CH2:10][CH2:9]1.C([OH:15])C>>[CH2:2]([S:6][CH:9]1[CH2:10][CH2:11][CH2:12][C:8]1=[O:15])[CH2:3][CH2:4][CH3:5]

참가 물질

5

반응물 4

HCID 702Ethanol2회HCID 8012ButanethiolHCID 70252ChlorocyclopentaneHCID 5360545Sodium

생성물 1

HCID 229313962-(Butylsulfanyl)cyclopentan-1-one

실험 절차

Absolute ethanol (600 ml) was added with metal sodium (13.8 g) and butylmercaptan (64.8 g). A solution of 2-chlorocyclopentane (71.1 g) in absolute ethanol (600 ml) was added to the mixture and then was allowed to stand overnight at a low temperature. The ethanol was removed from the mixture, and the residue was dissolved in ether. The resulting solution was neutralized with aqueous acetic acid solution, the solvent was evaporated, and the resultant was then subjected to distillation, thereby giving 2-buthylthiocyclopentanone (90 g).

후처리

  1. customThe ethanol was removed from the mixture
  2. dissolutionthe residue was dissolved in ether
  3. customthe solvent was evaporated
  4. distillationthe resultant was then subjected to distillation
  5. customgiving 2-buthylthiocyclopentanone (90 g)

출처 및 근거

ORD 기록
ord-48e0187831ea4486b732e499f7c4ad21
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07252849B2

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