3-Aminopyridine → 2-(2-pyridin-3-yl-2H-tetrazol-5-yl)pyridine

HRID 852316노트

반응식

HRID 852316 반응식
ClC1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[NH2:19]C1C=NC=CC=1.C1C=C(C=O)N=CC=1>>[N:19]1[CH:7]=[CH:6][CH:5]=[C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)[CH:3]=1

참가 물질

4

반응물 3

HCID 100093-AminopyridineHCID 142732-PyridinecarboxaldehydeHCID 99213692-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine

생성물 1

HCID 98778862-(2-pyridin-3-yl-2H-tetrazol-5-yl)pyridine

실험 절차

Following the procedure described in EXAMPLE 1 for the synthesis of 2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine, but using 3-amino pyridine (565 mg, 6.0 mmol) and 2-pyridyl carboxaldehyde (642 mg, 6.0 mmol), 2-(2-pyridin-3-yl-2H-tetrazol-5-yl)pyridine was obtained as an off white solid.

출처 및 근거

ORD 기록
ord-70fe5c54221e4415978cf6be25b46623
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07253190B2

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