Methanol → HCID 178498891, 화합물

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C[C:2]#[C:3][C:4]([O-:6])=[O:5].C[Si]([N:11]=[N+:12]=[N-:13])(C)C.[CH3:14]O>>[NH:11]1[CH:2]=[C:3]([C:4]([O:6][CH3:14])=[O:5])[N:13]=[N:12]1

참가 물질

반응물 3

HCID 887Methanol

HCID 78378Azidotrimethylsilane

HCID 6994510HCID 6994510, 화합물

생성물 1

HCID 178498891HCID 178498891, 화합물

반응 조건

온도: 105 °C

실험 절차

Methylpropiolate (20 g) and trimethylsilyl azide (68.6 g) were added to a pressure-resistant tube, and the mixture was stirred for 72 hours at 105° C. After allowing the mixture to be cooled to room temperature, methanol was added to the mixture, and the solvent was removed under reduced pressure, and the obtained residue was washed with diethylether/methanol to give methyl 1,2,3-triazole-4-carboxylate (22.7 g).