Methanol → N-[4-methoxy-4-(benzothiazol-2-yl)cyclohexa-2,5-dienylidene]4-methylbenzenesulphonamide

HRID 857073

반응식

HRID 857073 반응식
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[C:10]1[CH:15]=[CH:14][C:13]([NH:16][S:17]([C:20]2[CH:25]=[CH:24][C:23]([CH3:26])=[CH:22][CH:21]=2)(=[O:19])=[O:18])=[CH:12][CH:11]=1.[CH3:27][OH:28]>>[CH3:27][O:28][C:10]1([C:2]2[S:1][C:5]3[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=3[N:3]=2)[CH:11]=[CH:12][C:13](=[N:16][S:17]([C:20]2[CH:21]=[CH:22][C:23]([CH3:26])=[CH:24][CH:25]=2)(=[O:18])=[O:19])[CH:14]=[CH:15]1

참가 물질

3

반응물 2

HCID 887MethanolHCID 4380499N-[(4-benzothiazol-2-yl)phenyl]-4-methylbenzenesulfonamide

생성물 1

HCID 482713N-[4-methoxy-4-(benzothiazol-2-yl)cyclohexa-2,5-dienylidene]4-methylbenzenesulphonamide수율 73%

실험 절차

To the the sulfonamide (0.1 g) dissolved in methanol (2 mL) was added BTIB (1.1 eq.) in one portion as a solid. The resulting suspension was stirred at room temperature for 5 hours. The precipitate formed was collected on a filter, washed with ice cold methanol (2 mL) and dried under vacuum to give the title compound.

후처리

  1. additionwas added BTIB (1.1 eq.) in one portion as a solid
  2. customThe precipitate formed
  3. customwas collected on a filter
  4. washwashed with ice cold methanol (2 mL)
  5. customdried under vacuum

출처 및 근거

ORD 기록
ord-b951bb7129ed40e7a6235adac8bb8d48
출처 데이터셋
uspto-grants-2006_12
특허 번호
US07144893B2

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