Sodium Hydroxide → 2-(1H-imidazol-2-yl)benzonitrile
반응식
Cl.[NH:2]1[CH:6]=[CH:5][N:4]=[C:3]1[C:7]1[CH:14]=[CH:13][CH:12]=[CH:11][C:8]=1[C:9]#[N:10].[OH-].[Na+]>O>[NH:2]1[CH:6]=[CH:5][N:4]=[C:3]1[C:7]1[CH:14]=[CH:13][CH:12]=[CH:11][C:8]=1[C:9]#[N:10]참가 물질
4
실험 절차
To a solution of 2-(1H-imidazol-2-yl)-benzonitrile hydrochloride (3 g, 0.014 mol) in water (20 ml) was added sodium hydroxide solution (2.5 N, 5 ml). Filtration of the resultant precipitate and recrystallization from ethyl acetate gave 2-(1H-imidazol-2-yl)-benzonitrile; Anal. Calcd. For C10H7N3: C, 70.99; H, 4.17; N, 24.84. Found: C, 70.74; H, 4.08; N, 25.24.
후처리
- filtrationFiltration of the resultant precipitate and recrystallization from ethyl acetate
출처 및 근거
- ORD 기록
- ord-3d73e31051994e19a45e7161bbba3351
- 출처 데이터셋
- uspto-grants-2006_12
- 특허 번호
- US07144899B2
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