Tert-butyl 2-nitro-4-thien-3-ylphenylcarbamate → Tert-butyl [2-amino-4-(3-thienyl)phenyl]carbamate

HRID 859303

반응식

HRID 859303 반응식
[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:18]=[CH:17][S:16][CH:15]=2)=[CH:10][C:9]=1[N+:19]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[CH:18]=[CH:17][S:16][CH:15]=2)=[CH:10][C:9]=1[NH2:19])([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 1

HCID 66865115Tert-butyl 2-nitro-4-thien-3-ylphenylcarbamate

생성물 1

HCID 57717476Tert-butyl [2-amino-4-(3-thienyl)phenyl]carbamate

시약·촉매·용매 1

HCID 935Nickel촉매

실험 절차

Prepared from (2-nitro-4-thiophen-3-yl-phenyl)-carbamic acid tert.-butyl ester (Example B2) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a white solid (278 mg).

출처 및 근거

ORD 기록
ord-a45ec6fe03e04604aacc357a75602db2
출처 데이터셋
uspto-grants-2006_12
특허 번호
US07151098B2

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