Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Azidobenzoyl chloride → {3-[3-(3-Azido-phenyl)-3-oxo-propionylamino]-biphenyl-4-yl}-carbamic acid tert.-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Azidobenzoyl chloride | HCID 22224783 | — |
| 반응물 | N-(3-Amino[1,1'-biphenyl]-4-yl)-carbamic Acid tert-Butyl Ester | HCID 57717454 | — |
| 반응물 | 3-(3-Azido-phenyl)-3-oxo-propionic acid ethyl ester | HCID 86587996 | — |
| 생성물 | {3-[3-(3-Azido-phenyl)-3-oxo-propionylamino]-biphenyl-4-yl}-carbamic acid tert.-butyl ester | HCID 86587995 | — |
반응 단계
Prepared (3-amino-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example G9) (569 mg, 2 mmol) and 3-(3-azido-phenyl)-3-oxo-propionic acid ethyl ester (700 mg, 3 mmol; prepared from 3-azido-benzoyl chloride (Bioorg. Chem 1986, 134) using the procedure described in Synthesis, 1993, 290, method A; MS (EI) 233 (M+)) according to the general procedure K. Obtained as an orange solid (367 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07151098B2 |
| 출처 데이터셋 | uspto-grants-2006_12 |
| ORD ID | ord-6738dfcd3f75403ba3c74f3da4cafcd9 |
| 출처 메모 | uspto-grants-2006_12 |