Tetra-n-butylammonium tribromide → HCID 58764135, 화합물
반응식
[Br-:1].[Br-].[Br-].C([N+](CCCC)(CCCC)CCCC)CCC.C([N+](CCCC)(CCCC)CCCC)CCC.C([N+](CCCC)(CCCC)CCCC)CCC.[CH2:55]([O:57][C:58]1[CH:59]=[CH:60][C:61]([CH2:65][CH3:66])=[C:62]([OH:64])[CH:63]=1)[CH3:56]>C(Cl)(Cl)Cl>[Br:1][C:59]1[C:58]([O:57][CH2:55][CH3:56])=[CH:63][C:62]([OH:64])=[C:61]([CH2:65][CH3:66])[CH:60]=1참가 물질
4
실험 절차
A solution of tetrabutyl ammonium tribromide (9.9 g, 20.5 mmol) in CHCl3 (60 mL) was added to a stirred solution of 5-ethoxy-2-ethyl-phenol (3.1 g, 18.6 mmol) dissolved in CHCl3 (90 mL). The reaction mixture was stirred for 30 mins and then quenched with 5% solution of sodium thiosulfate (30 mL). The biphasic mixture was stirred for 30 mins and then the layers were separated. The organic layer was washed with 1 N HCl, brine, dried over Na2SO4 and concentrated to a red oil. Purification by flash column chromatography (0% to 15% EtOAc in hexanes) gave the product as an oil (2.6 g, 58%).