Phenol → 2-Naphthyloxy proline amide

HRID 862167

반응식

HRID 862167 반응식
FC(F)(F)C(O)=O.C([NH:12][C:13](=[O:26])[C@@H:14]1[CH2:18][C@H:17](OC2C=CC=CC=2)[CH2:16][NH:15]1)(C)(C)C.[CH:27]1[C:36]2[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH:30]=[CH:29][C:28]=1[OH:37].C1(O)C=CC=CC=1>>[CH:27]1[C:36]2[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=2)[CH:30]=[CH:29][C:28]=1[O:37][N:15]1[CH2:16][CH2:17][CH2:18][C@H:14]1[C:13]([NH2:12])=[O:26]

참가 물질

4

반응물 3

HCID 996PhenolHCID 86632-NaphtholHCID 22862000n-t-Butyl-4(s)-phenoxy-l-prolineamide trifluoroacetic acid salt

생성물 1

HCID 228619932-Naphthyloxy proline amide

실험 절차

Following substantially the same procedure for synthesizing N-t-butyl-4(S)-phenoxy-L-prolineamide trifluoroacetic acid salt as outlined in Example 1, Steps 6 through 8, but substituting 2-naphthol for the phenol used therein, the 2-naphthyloxy proline amide was produced.

출처 및 근거

ORD 기록
ord-6ce8b119f8fb4cf58944441985847126
출처 데이터셋
uspto-grants-1998_02
특허 번호
US05717097

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