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Sodium Hydroxide → HCID 70076641, 화합물

HRID 862427
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HRID 862427 반응식
[ClH:1].[O:2]1[CH2:7][CH2:6][N:5]([N:8]=[CH:9][C:10]2[CH:34]=[CH:33][C:13]([C:14]([NH:16][C:17]3[CH:26]=[C:25]4[C:20]([CH2:21][CH2:22][CH:23]([CH2:27][C:28]([O:30]CC)=[O:29])[CH2:24]4)=[CH:19][CH:18]=3)=[O:15])=[CH:12][CH:11]=2)[CH2:4][CH2:3]1.[OH-].[Na+]>C(O)C>[ClH:1].[O:2]1[CH2:7][CH2:6][N:5]([N:8]=[CH:9][C:10]2[CH:11]=[CH:12][C:13]([C:14]([NH:16][C:17]3[CH:26]=[C:25]4[C:20]([CH2:21][CH2:22][CH:23]([CH2:27][C:28]([OH:30])=[O:29])[CH2:24]4)=[CH:19][CH:18]=3)=[O:15])=[CH:33][CH:34]=2)[CH2:4][CH2:3]1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 70076057HCID 70076057, 화합물

생성물 1

HCID 70076641HCID 70076641, 화합물수율 63.7%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

The compound (0.15 g) obtained in Example 1 was suspended in ethanol (10 ml), a 1N aqueous sodium hydroxide solution (1.5 ml) was added, and the mixture was stirred overnight. The solvent was distilled off under reduced pressure, a 3N aqueous hydrochloric acid solution was added, and the formed precipitate was filtered, washed with water, and dried under reduced pressure to obtain the entitled compound (0.09 g).

후처리

  1. distillationThe solvent was distilled off under reduced pressure
  2. additiona 3N aqueous hydrochloric acid solution was added
  3. filtrationthe formed precipitate was filtered
  4. washwashed with water
  5. customdried under reduced pressure

출처 및 근거

ORD 기록
ord-f0d1e83f03a3478fa3ccb1be3df8cd4b
출처 데이터셋
uspto-grants-1998_02
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US05719145

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