Benzaldehyde → 4-Benzylamino-1-Butanol

HRID 862781노트

반응식

HRID 862781 반응식
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][OH:6].[CH:7](=O)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>O=[Pt]=O.CCO>[C:8]1([CH2:7][NH:1][CH2:2][CH2:3][CH2:4][CH2:5][OH:6])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

5

반응물 2

HCID 240BenzaldehydeHCID 258684-Amino-1-butanol

생성물 1

HCID 17900184-Benzylamino-1-Butanol

시약·촉매·용매 2

HCID 345198Adams' catalyst촉매HCID 702Ethanol용매

실험 절차

Combine 4-amino-butan-1-ol (8.9 gm-0.1 mol), benzaldehyde (10.6 gm-0.1 mol), EtOH (100 ml) and PtO2 (0.3 gm), and hydrogenate the mixture at 45 lbs./sq.in. until H2 is no longer taken up. Filter, evaporate the solvent (in vacuo) to yield 17.7 gm of the desired compound. Rf is 0.70 (eluted from silica gel with 10% conc. NH3 /CH3OH).

후처리

  1. filtrationFilter
  2. customevaporate the solvent (in vacuo)

출처 및 근거

ORD 기록
ord-903fe23eb0b0453cbd0c0b252b58ca0a
출처 데이터셋
uspto-grants-1998_02
특허 번호
US05719193

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