Water → Ethanediamide, N1,N2-bis(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-

HRID 866523

반응식

HRID 866523 반응식
[C:1]1(=[O:11])O[C:4](=[O:5])[C:3]2=[CH:7][CH:8]=[CH:9][CH:10]=[C:2]12.[C:12]([NH:18][NH2:19])(=[O:17])[C:13]([NH:15][NH2:16])=[O:14].[OH2:20]>C1(C)C(C)=CC=CC=1>[C:4]1(=[O:5])[N:16]([NH:15][C:13]([C:12]([NH:18][N:19]2[C:1](=[O:11])[C:2]3=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]3[C:4]2=[O:5])=[O:17])=[O:14])[C:1](=[O:20])[C:2]2=[CH:10][CH:9]=[CH:8][CH:7]=[C:3]12

참가 물질

5

반응물 3

HCID 962WaterHCID 6811Phthalic AnhydrideHCID 13826Oxalic acid, dihydrazide

생성물 1

HCID 113193Ethanediamide, N1,N2-bis(1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)-수율 94%

시약·촉매·용매 1

HCID 7237O-Xylene용매

실험 절차

Two moles of phthalic anhydride (296g) and one mole of oxalic dihydrazide (118 g) in xylene (2.5 l) were heated at reflux until two moles of water were removed (about 24 hours). The product was filtered and dried at 50° C. N,N'-bis(phthalimido)-oxamide was obtained in 94-6 percent yield. The compound was a white solid melting at 295° C (dec.) and having the following elemental analysis by weight percent:

후처리

  1. customwere removed (about 24 hours)
  2. filtrationThe product was filtered
  3. customdried at 50° C

출처 및 근거

ORD 기록
ord-b37e282ca629479f922fa055cd857357
출처 데이터셋
uspto-grants-1978_07
특허 번호
US04100132

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