Piperidine → HCID 178426457, 화합물

HRID 867304

반응식

HRID 867304 반응식
C1CCNCC1.Cc1cc(C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc(N)c1Br>CS(C)=O.O=C(O)C(=O)Nc1c(F)cccc1F.O=P([O-])([O-])[O-].[Cu][I].[K+].[K+].[K+]>Cc1cc(C#N)cc(C)c1Oc1nc(Nc2ccc(C#N)cc2)nc(N)c1N1CCCCC1

참가 물질

7

반응물 2

HCID 8082PiperidineHCID 193962Etravirine

생성물 1

HCID 178426457HCID 178426457, 화합물수율 0%

시약·촉매·용매 4

HCID 62657Potassium Phosphate, Tribasic시약HCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)촉매HCID 28710784[(2,6-Difluorophenyl)carbamoyl]formic acid촉매HCID 679Dimethyl Sulfoxide용매2회

반응 조건

온도
80 °C

후처리

  1. additionThe reaction vials were then cooled to r.t. and diluted with 100 μL of 5% AcOH in DMSO, containing 1,3,5-trimethoxybenzene (0.005M) and were shaken vigorously.
  2. aliquot25 microliter of resulting solution is taken
  3. additionTo the 25 microliter aliquot 700 microliter of MeCN was added prior to UPLC-MS Analysis

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ORD 기록
ord-8b80e81445364184a2a17f9f21689da8
출처 데이터셋
Figure 4 from Chemistry informer libraries
원본 링크
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연결된 노트

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