2-Chlorobenzoic Acid → Methyl 2-chlorobenzoate
반응식
[N+](=[CH2:3])=[N-].[Cl:4][C:5]1[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=1[C:7]([OH:9])=[O:8]>CCOCC>[Cl:4][C:5]1[CH:13]=[CH:12][CH:11]=[CH:10][C:6]=1[C:7]([O:9][CH3:3])=[O:8]참가 물질
4
실험 절차
An excess solution of diazomethane in ether was added to an ice-cooled and stirred solution of o-chlorobenzoic acid (7.6 g, 48.6 mmol) in 50 ml of ether. After concentration, the residue was distilled under reduced pressure to give a colorless transparent oil of methyl o-chlorobenzoate (6.0 g, 35.2 mmol, yield 72.4%, b.p. 92°-93° C./7 mmHg), which was assigned the structure by the following data:
후처리
- temperaturecooled
- concentrationAfter concentration
- distillationthe residue was distilled under reduced pressure
출처 및 근거
- ORD 기록
- ord-3266c0d51b2249708da94ad3e0457107
- 출처 데이터셋
- uspto-grants-1988_10
- 특허 번호
- US04775692
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